{"@context":{"aiiso":"http:\/\/purl.org\/vocab\/aiiso\/schema#","arm":"https:\/\/ld4p.github.io\/arm\/core\/ontology\/0.1\/","bf":"http:\/\/id.loc.gov\/ontologies\/bibframe\/","bib":"https:\/\/bibliotek-o.org\/","bibo":"http:\/\/purl.org\/ontology\/bibo\/","cito":"http:\/\/purl.org\/spar\/cito\/","classSchemes":"http:\/\/id.loc.gov\/vocabulary\/classSchemes","dbo":"http:\/\/dbpedia.org\/ontology\/","dce":"http:\/\/purl.org\/dc\/elements\/1.1\/","dcmitype":"http:\/\/dublincore.org\/documents\/2000\/07\/11\/dcmi-type-vocabulary\/#","dcterms":"http:\/\/purl.org\/dc\/terms\/","ebucore":"http:\/\/www.ebu.ch\/metadata\/ontologies\/ebucore\/ebucore","edm":"http:\/\/www.europeana.eu\/schemas\/edm\/","foaf":"http:\/\/xmlns.com\/foaf\/spec\/#","frap":"http:\/\/purl.org\/cerif\/frapo","identifiers":"http:\/\/id.loc.gov\/vocabulary\/identifiers","ids":"http:\/\/id.loc.gov\/vocabulary\/identifiers\/","opaque":"http:\/\/opaquenamespace.org\/","pcdm":"http:\/\/pcdm.org\/models#","phaidra":"https:\/\/phaidra.org\/ontology\/","rdam":"http:\/\/rdaregistry.info\/Elements\/m\/","rdau":"http:\/\/rdaregistry.info\/Elements\/u\/","rdax":"http:\/\/rdaregistry.info\/Elements\/x\/","rdf":"http:\/\/www.w3.org\/1999\/02\/22-rdf-syntax-ns#","rdfs":"https:\/\/www.w3.org\/TR\/rdf-schema\/","relators":"http:\/\/id.loc.gov\/vocabulary\/relators","role":{"@context":{"aut":{"@container":"@list","@id":"http:\/\/id.loc.gov\/vocabulary\/relators\/aut"}}},"schema":"http:\/\/schema.org\/","skos":"http:\/\/www.w3.org\/2004\/02\/skos\/core#","skosxl":"http:\/\/www.w3.org\/2008\/05\/skos-xl"},"@id":"https:\/\/door.donau-uni.ac.at\/o:5152","bf:note":[{"@type":"bf:Note","skos:prefLabel":[{"@language":"eng","@value":"Background: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has\nbecome a major global concern. As of writing this manuscript, there are over 224 million cases\ndiagnosed, and 4.5 million recorded deaths with the Coronavirus Disease 2019 (COVID-19).\nObjectives: This article reviews the studies conducted on SARS-CoV-2 pathogenesis,\ntransmission, and different clinical manifestations.\nMethods: An extensive online search was conducted on PubMed and Google Scholar search\nengines. The following keywords and their combinations were used to complete this review:\n“SARS-CoV-2”, “COVID-19”, “virology”, “mechanism of action”, “transmission”, “clinical\nmanifestations”, “laboratory findings”, and “comorbidities.”\nResults: The SARS-CoV-2 spike glycoprotein recognizes the human angiotensin-converting\nenzyme 2 receptors, and through that, the virus can enter its host cell. The virus is mainly\ntransmitted via respiratory and or airborne droplets. The severity of the COVID-19 clinical\nmanifestations relies on the associated comorbidities and or old age, which ranges from little-\nto-no symptoms to severe and critical conditions. Fever, loss of appetite and or smell, fatigue,\nand dry cough are among the most reported symptoms. Underlying conditions may lead to\nsevere or critical stages of COVID-19.\nConclusion: The SARS-CoV-2 nucleocapsid and receptor-binding domain could be two\npotential targets for future vaccines and drugs. It appears that the virus is adapting to each\nregion’s specific environment; therefore, new endemic variants are forming."}]}],"bf:provisionActivity":[{"@type":"bf:Publication","bf:agent":[{"@type":"schema:Organization","schema:name":[{"@value":"Mazandaran University of Medical Research"}]}]}],"dce:subject":[{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"COVID-19"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"SARS-CoV-2"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Etiology"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Transmission"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Signs"}]},{"@type":"skos:Concept","skos:prefLabel":[{"@language":"eng","@value":"Symptoms"}]}],"dce:title":[{"@type":"bf:Title","bf:mainTitle":[{"@language":"eng","@value":"A Narrative Review of SARS-CoV-2 Pathogenesis, Transmission, and Clinical Manifestations"}]}],"dcterms:issued":["2022-08"],"dcterms:language":["eng"],"dcterms:type":[{"@type":"skos:Concept","skos:exactMatch":["https:\/\/pid.phaidra.org\/vocabulary\/69ZZ-2KGX"],"skos:prefLabel":[{"@language":"eng","@value":"Text"},{"@language":"deu","@value":"Text"}]}],"ebucore:filename":["mazums-pbr-v8n3p167-en.pdf"],"ebucore:hasMimeType":["application\/pdf"],"edm:hasType":[{"@type":"skos:Concept","skos:exactMatch":["https:\/\/pid.phaidra.org\/vocabulary\/VKA6-9XTY"],"skos:prefLabel":[{"@language":"eng","@value":"journal article"},{"@language":"deu","@value":"Wissenschaftlicher Artikel"}]}],"edm:rights":["http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"],"rdam:P30004":[{"@type":"ids:doi","@value":"10.18502\/pbr.v8i3.11031"}],"rdau:P60193":[{"@type":"schema:CreativeWork","bibo:issue":["3"],"bibo:volume":["8"],"dce:title":[{"@type":"bf:Title","bf:mainTitle":[{"@language":"deu","@value":"Pharmaceutical and Biomedical Research"}]}]}],"role:aut":[{"@type":"schema:Person","schema:affiliation":[{"@type":"schema:Organization","schema:name":[{"@value":"Tehran University of Medical Sciences"}],"skos:exactMatch":["https:\/\/ror.org\/01c4pz451"]}],"schema:familyName":[{"@value":"Sharifan"}],"schema:givenName":[{"@value":"Amin"}],"skos:exactMatch":[{"@type":"ids:orcid","@value":"0000-0003-0571-5964"}]}]}